TB-500

TB-500 (Ac-LKKTETQ) is a synthetic fragment corresponding to the actin-binding domain of Thymosin Beta-4 (Tβ4), a ubiquitous 43-amino acid peptide involved in actin polymerization dynamics and intracellular cytoskeletal regulation. Research has documented TB-500’s roles in endothelial cell migration, angiogenesis, cardiomyocyte survival, wound healing, and inflammation modulation across dermal, tendinous, cardiac, and neural tissue models. Its compact size relative to full-length Tβ4 retains key bioactivity and may offer improved tissue penetration in systemic research models. Available in 5mg (TB.05) and 10mg (TB.10) formats.

Molecular Information

CAS Number	885340-08-9 (TB-500 fragment)
Molecular Formula	C₃₈H₆₈N₁₀O₁₄ (Ac-LKKTETQ)
Molecular Weight	~4963 g/mol (full sequence context)
Purity	≥98% (HPLC)
Appearance	White lyophilized powder
Storage Form	Lyophilized peptide

Storage Information

Store in a refrigerated environment free of exposure to sunlight, moisture, or excessive heat.

Quality Assurance & Supplier Commitment

We maintain longstanding relationships with leading peptide lyophilizers and raw material suppliers, selected through an exhaustive vetting process that evaluates manufacturing practices, analytical capabilities, and regulatory compliance. Our API sourcing protocol includes certificate of analysis review, third-party analytical testing, and periodic supplier audits to ensure consistent purity, potency, and sterility standards across all product lines.

Each batch undergoes meticulous quality control verification prior to release, including HPLC purity analysis, mass spectrometry confirmation, and endotoxin testing where applicable. Our commitment to sourcing integrity ensures researchers receive material of the highest available quality.