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MOTS-C (Mitochondrial Open reading frame of the Twelve S rRNA-c) is a 16-amino acid peptide encoded within the mitochondrial 12S rRNA gene. It functions as a mitochondria-derived signaling molecule (mitokine) with demonstrated activity in regulating AMPK pathways, glucose metabolism, and fatty acid oxidation. Research in rodent models has shown its capacity to improve insulin sensitivity, reduce obesity-related metabolic dysfunction, and attenuate age-related physical decline. Recent studies further implicate MOTS-C in nuclear gene regulation, positioning it as a mitochondrial-to-nuclear signaling peptide of broad research interest. Batch ID: MT.10.
Molecular Information
|
CAS Number |
1448585-24-7 |
|
Molecular Formula |
C₈₉H₁₆₀N₃₂O₂₂S₂ (human sequence) |
|
Molecular Weight |
2174.5 g/mol |
|
Purity |
≥98% (HPLC) |
|
Appearance |
White lyophilized powder |
|
Storage Form |
Lyophilized peptide |